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Virginia E. Kimonis, MD

We are a molecular genetics lab within the Division of Genetics & Genomic Medicine at UC Irvine School of Medicine Department of Pediatrics.

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Kimonis Lab

The Kimonis Laboratory is a molecular genetics lab within the Division of Genetics & Genomic Medicine at UCI School of Medicine Department of Pediatrics.

We are scientists and doctors studying genetic causes of and new treatments for muscle diseases, and other rare genetic disorders such as lysosomal storage diseases, Prader-Willi, and mitochondrial diseases The Kimonis laboratory is particularly interested in Hereditary Inclusion body myopathies including Inclusion body myopathy, Paget disease of bone,  frontotemporal dementia and amyotrophic lateral sclerosis associated with Valosin Containing Protein (VCP) mutations (also known as VCP disease,  IBMPFD or multisystem proteinopathy) and also Inclusion body myopathy associated with HSPB8 gene mutations.

If you or a member of your family has one of the disorders that we are studying and you have questions, comments, or would like to participate in a study, please contact us.


A Phase 2,Pilot Study to Assess RM-493, a Melanocortin 4 Receptor (MC4R) Agonist in Prader-Willi Syndrome
The Kimonis Lab hosted a Pompe disease outreach event on June 4, which attracted dozens of participants.
Connecting the Dots: Complex Chronic Pain in Children (Ehlers Danlos syndrome)
Dr. Virginia Kimonis and fellow UC Irvine researchers are dedicated to finding genetic clues, giving new hope to families.
Dr. Virginia Kimonis is an author of the paper, "Effect of Genetic Subtypes and Growth Hormone Treatment on Bone Mineral Density in Prader-Willi Syndrome."
See all latest publications »