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UC Irvine
FACULTY
Academic Address:
For OC Kids, CHOC-UCI
Neurodevelopmental Center
1915 W. Orangewood Ave. Suite 200
Zot 4482
Orange, CA 92868
Email:
forockids@uci.edu
Pauline A. Filipek, M.D.
- Faculty Profile
- Dr. Filipek received her BS from Georgetown University and her MD from Georgetown
University School of Medicine. She completed a pediatric residency, including a chief residency, at the
University of Massachusetts Medical Center, and a (child) neurology residency and MRI-Morphometry Fellowship
at Massachusetts General Hospital/Harvard Medical School. She remained at MGH/HMS on
faculty until she was recruited to UCI Departments of Pediatrics and Neurology in 1994.
Dr. Filipek clinically specializes in children with developmental disorders. She has received many grant awards from the National Institutes of Health and other foundations
such as the National Alliance for Autism Research. Most recently, Dr. Filipek was the recipient of a $6+ million
grant from the Children and Families Commission of Orange County to improve early recognition and treatment of
young children with autism. Dr. Filipek served as the Chair of the American Academy of Neurology/Child Neurology
Society committee to determine Practice Parameter: Screening and Diagnosis of Autism. She also
served on the National Academy of Science Committee on Educational Interventions for Autistic Children.
- Position:
- Associate Professor of Clinical Pediatrics
- - Pediatric Neurology Division
- Associate Professor of Clinical Neurology
- EDUCATION
- Medical School Education:
- Georgetown University School of Medicine
- Internship:
- University of Massachusetts Medical School - Pediatrics
- Residency:
- University of Massachusetts Medical School - Pediatrics
- Massachusetts General Hospital/Harvard Medical School - (Child) Neurology
- Fellowship:
- Massachusetts General Hospital/Harvard Medical School - MRI Morphometry
- MEMBERSHIPS & AFFILIATIONS
- Board Certifications:
- American Board of Pediatrics
- American Board of Psychiatry and Neurology, with Special Competence in Child
Neurology
- Professional Societies:
- American Academy of Pediatrics
- American Academy of Neurology
- Child Neurology Society
- American Neurological Association
- Society for Pediatric Research
- Society for Neuroscience
- RESEARCH
- Interests:
- Autism and other developmental disorders.
- Specific Projects:
- Dr. Filipek founded For OC Kids with a grant from the Proposition 10 Children and
Families Commission of Orange County to create the Neurodevelopmental Center to serve children and families with
autism and other developmental disorders. She is particularly interested in the identification of the
early subtle signs of autism in infancy.
- SELECTED PUBLICATIONS
- 1. Filipek PA, Accardo PJ, Baranek GT, Cook EH Jr, Dawson G, Gordon B, Gravel JS, Johnson CP,
Kallan RJ, Levy SE, Minshew NJ, Ozonoff S, Prizant BM, Rapin I, Rogers SJ, Stone WL, Teplin SW, Tuchman RF, Volkmar FR.
The screening and diagnosis of autistic spectrum disorders. Journal of Autism and Developmental Disorders. 29: 437-482, Dec 1999.
- 2. American Academy of Neurology. Practice parameter: Screening and diagnosis of autistic
spectrum disorders. Neurology 55(4): 468-479, 22 Aug 2000.
- 3. Owley T, McMahon W, Cook E, Laulhere T, South M, Mays L, Steele E, Lainhart J, Modahl
C, Ozonoff S, Risi S, Lord C, Leventhal B, Filipek P. A multi-site, double-blind, placebo-controlled trial of
porcine secretin in autism. Journal of the American Academy of Child and Adolescent Psychiatry, 40: 1293-1299, 2001.
- 4. Filipek PA, Juranek J, Gargus JJ, Smith M, Ramos ER, Mays LZ, Bocian M, Masser-Frye D,
Laulhere TM, Modahl CM, Spence MA. Evidence of mitochondrial dysfunction in autistic patient with 15q inverted
duplication. Annals of Neurology, 53: 801-804, 2003.
- 5. Goldberg WA, Osann K, Filipek PA, Laulhere T, Jarvis K, Modahl C, Flodman P, Spence MA.
Language and other regression: Assessment and timing. Journal of Autism and Developmental Disorders, 33:
607-626, 2003.
- 6. Filipek PA, Juranek J, Nguyen MT, Cummings C, Gargus JJ. Relative carnitine deficiency
in autism. Journal of Autism and Developmental Disorders, 34(6): 615-623, 2004.
- 7. Goldberg WA, Jarvis KL, Osann K, Laulhere TM, Straub C, Thomas E, Filipek PA, Spence MA.
Early social communication behaviors in the younger siblings of children with autism. Journal of Autism and
Developmental Disorders 2005; 35: 657-664.
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